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Information and registration: http://bcnvph.org
This Summer School provides a thorough overview and hands-on experience in state-of-the-art Virtual Physiological Human (VPH) research. The key concepts of this methodological and technological framework will be presented using illustrative cases and enriched with hands-on analysis under supervision of the experts.
The School is jointly organised by the Philips - UPF CardioFunXion Marie Curie European Industrial Doctorate Program and The Virtual Physiological Human Institute, and the support of the Spanish Network of Excellence in Biomechanics.
New publication about patient-specific estimates of vascular and placental properties in growth-restricted fetuses based on a model of the fetal circulation
Intrauterine growth restriction (IUGR) due to placental insufficiency is associated with blood-flow redistribution in order to maintain perfusion to the brain. However, some hemodynamic parameters that might be more directly related to staging of the disease cannot be measured non-invasively in clinical practice. For this, we developed a patient-specific model of the fetal circulation to estimate vascular properties of each individual. A lumped model of the fetal circulation was developed and personalized using measured echographic data from 37 normal and IUGR fetuses to automatically estimate model-based parameters. The estimated model-based placental and brain resistances were respectively increased and reduced in IUGR fetuses while placental compliance was increased in IUGR fetus. Umbilical and middle cerebral arteries PIs were most associated with both placental resistance and compliance, while uterine artery PI was more associated with the placental compliance. The logistic regression analysis showed that the model added significant information to the traditional analysis of Doppler waveforms for predicting adverse outcome in IUGR. The proposed patient-specific computational model seems to be a good approach to assess hemodynamic parameters than cannot be measured clinically.
We congratulate Dr. Patricia García Cañadilla, who defended her dissertation on July 2nd. Well done Patricia ;).
New publication about Estimation of Purkinje Trees from Electro-Anatomical Mapping of the Left Ventricle Using Minimal Cost Geodesics
Authors: Rubén Cárdenes, Rafael Sebastian, David Soto-Iglesias, Antonio Berruezo, Oscar Camara